Heart disease is the number one killer in the United States. But one professor at the University of Pittsburgh might soon mend broken hearts, is the most literal sense anyway. Pittsburgh professor Yadong Wang figured out that by delivering a critical growth factor directly to the blood vessels in a non-invasive way, he could potentially eliminate the need for open-heart surgery someday. So far, the treatment has worked in the lab only in animal studies. When researchers injected a growth factor under the skin of mice, the blood vessels began to regrow. “We had structures that resembled arterioles - small arteries that lead to a network of capillaries,” Wang said in a statement. The fact that the blood vessels showed signs of repair is significant because currently once tissue is damaged after a heart attack, a patient has to either get a stent or have bypass surgery. Being able to repair damaged tissue and prevent further scarring, would enable doctors to keep the heart … [Read more...] about How regrowing blood vessels could lead to better heart disease treatment in the future
Help prevent heart disease
Two fuzzy lessons of the heart. Scientists hope to reduce the damages caused by heart attacks by inducing hibernation in squirrels and by synthesizing a chemical found in bear bile. 1. A team from the University of Alaska Fairbanks has figured out a way to send Arctic ground squirrels (Spermophilus parryii, pictured) into and out of hibernation at will – by identifying the switch that triggers that torpor. The effects of hibernation on squirrels are drastic: their oxygen consumption dips to 1% of what it normally is and their body temperature falls below freezing. Inducing hibernation-like states in patients could buy surgeons critical minutes when performing operations or save lives after a heart attack. Turns out, the hibernation switch in squirrels is a receptor on brain cells for the ‘drowsiness’ neurotransmitter adenosine, which sends us to sleep by building up gradually in the brain during the day, New Scientist explains. By blocking it using a chemical called … [Read more...] about Squirrels and bears help fight heart attack damages
A new report in the journal Pediatrics discusses a screening that could help test for congenital heart disease in infants, and possibly save lives. Research from the Centers for Disease Control and Prevention shows that congenital heart defects is one of the biggest causes of infant death during a baby's first year of life. A screening called pulse oximetry uses sensors to test an infant's oxygen level. Often times, the sensors are placed on the hand and foot. A low oxygen level could indicate a heart condition in an infant. According to Shari Roan from the Los Angeles Times: In a report published online Sunday in the journal Pediatrics, the doctors propose nationwide screening for critical congenital heart disease using pulse oximetry, a probe placed on a hand and a foot that uses a light source and sensor to measure oxygen in the blood. Low oxygen levels signal the need for further testing to look for a heart-related problem. In a prepared statement, lead study author Dr. … [Read more...] about Could a new screening help identify heart problems for newborns?
An international team of researchers say that anti-inflammatory drugs could be used to prevent and treat coronary heart disease, the world's leading cause of death. Led by University College London professors Juan Pablo Casas, Aroon Hingorani, and Daniel Swerdlow, the researchers sought to better understand the connection between inflammation and atherosclerosis, the buildup of fatty deposits on artery walls that causes the disease. Specifically, the researchers focused on a signaling protein in the blood called the interleukin-6 receptor. They found that it increased inflammatory response -- until now, no one had identified an inflammatory agent responsible for the disease -- and that an existing anti-inflammatory drug was able to act on it. "This study provides robust evidence that IL6R is implicated in coronary heart disease," said study co-author Brendan Keating. "Furthermore, our analysis showed that an existing anti-inflammatory drug, acting on … [Read more...] about Anti-inflammatory drugs may prevent heart disease
The U.S. announced on Tuesday an unprecedented drug trial aimed at preventing Alzheimer's, a disease that gradually causes dementia. The experiment is unusual for two reasons: The drug will be administered to subjects who are ostensibly healthy. A majority of them will, however, be genetically predisposed to develop the disease. Also, it will be one of the few experiments to be conducted on people with a genetic predisposition to any disease. The subjects will mostly be members of the world's largest family afflicted with Alzheimer's. In this Colombian family, who reside in and around Medellin, those who have a specific gene mutation normally show first Alzheimer's symptoms at 45 and full dementia at 51. Eventually, not only do their memories fade, but also their ability to move, eat and communicate. While the whole clan number 5,000, the $100 million, five-year trial, which begins in 2013, will be conducted on 300 subjects, some as young as 30. A few Americans unrelated to the family … [Read more...] about First large-scale trial of Alzheimer’s prevention drug announced
When you think of animals saving people’s lives, you probably picture a dolphin rescuing some ailing swimmer from drowning, or a Lassie-style dog pulling a toddler out of a well. In fact, the big lifesaver from the animal kingdom may just turn out to be one of the more unusual suspects out there: the tiny blood-sucking arachnid known as the tick.More commonly thought of as the carrier of various tick-borne diseases, including rickettsia and ebola, a new study from the U.K.’s University of Oxford suggests that tick saliva could actually be an invaluable weapon for helping fight inflammation-based pathologies like heart disease.“We have developed a method of rapidly identifying and characterizing proteins in tick saliva by cloning tick salivary gland genes into yeast,” Professor Shoumo Bhattacharya, lead author of a paper on the research, told Digital Trends. “We have used this method to identify tick saliva proteins, called evasins, that bind and neutralise … [Read more...] about Oxford scientists think the next big weapon in the fight against heart disease is… tick spit?
Research supports the idea that high fiber diets help to fight against the cardiovascular disease risk and may also result in longer and healthier lives. High fiber diets are a good way to keep your heart healthy and a shift towards this diet means a completely new lifestyle which must be adopted by the young as well as the middle aged. According to a recent study, adults who had a high fiber intake in their daily lives had a lower chance of developing any cardiovascular disease as compared to those who had no fibre rich diets. This study proves to be quite helpful and will help people make changes in their unhealthy eating habits and also this is the first study of its kind which studies the impact of high fiber intake. Get the Free Tracker App to find a Nintendo Switch in Stock “It’s long been known that high fiber diets can help people lose weight, lower cholesterol and improve hypertension,” said Donald M. Lloyd-Jones, corresponding author of the study. … [Read more...] about High-fiber Diet Helps Prevent Heart Diseases
A new study reveals that CPAP machines which are designed to help sleep apnea sufferers do not reduce the risk of heart attack or stroke in the patients, but help them breathe more easily during sleep. Get the Free Tracker App to find a Luvabella in Stock Sleep apnea, as the name suggests, is a sleep disorder which is characterized by momentarily stoppages in breathing during sleep. The condition can cause sleep disturbance and even lead to more chronic conditions like heart disease, high blood pressure, stroke and Type 2 diabetes. A CPAP machine or continuous positive airway pressure therapy is usually recommended for sleep apnea patients, which consists of a hose and a mask. The machine keeps the airway open by providing constant and steady air pressure to a patient’s throat. A new research has found that CPAP machines don’t prevent heart attack or strokes in patients with moderate to severe sleep apnea and existing cardiovascular disease. The impact is no better … [Read more...] about CPAP Machines Do Not Prevent Heart Attacks In Sleep Apnea Patients, Study Finds
Vegetable oil is widely known for its health benefits and there would be many people who have stopped using animal fat such as butter and cheese and replaced them with vegetable oil which is low in saturated fat. But a new research suggests that vegetable oil may help lower cholesterol levels but it cannot reduce the risk of heart disease. Get the Free Tracker App to find a SNES Classic in Stock Prevention from heart disease is something people expect from vegetable oil but not every kind of oil extracted from seeds contributes in achieving this goal. Vegetable oils that are rich in linoleic acid such as soybean, canola and corn oil are in fact having adverse effects on your heart health. A team of researchers led by medical investigator Chris Ramsden examined data from a trial carried out from 1968 to 1973 that involved more than 9,000 people living in nursing homes and mental hospitals.The participants were divided into two groups. During the course of almost four years, one … [Read more...] about Replacing Butter With Vegetable Oil Does Not Reduce Heart Disease Risk, Says Study
Men with grey hair may be at higher risk of chronic heart disease, a new research suggests. Get the Free Tracker App to find a Luvabella in Stock Grey hair might be an early indicator of heart problem in men. Researchers say that grey hair and atherosclerosis - hardening and narrowing of the arteries – are caused by the similar processes in body such as impaired DNA repair, oxidative stress, inflammation, hormonal changes and deterioration of functional cells. Ignoring this marker could lead to devastating consequences. “Ageing is an unavoidable coronary risk factor and is associated with dermatological signs that could signal increased risk,” said Dr Irini Samuel, a cardiologist at Cairo University, Egypt. “More research is needed on cutaneous signs of risk that would enable us to intervene earlier in the cardiovascular disease process.”The findings stem from an analysis that looked at more than 500 male participants. These participants were … [Read more...] about Grey Hair Could Be A Warning Sign For Heart Disease In Men